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1ny7
From Proteopedia
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| - | [[Image:1ny7.gif|left|200px]] | + | [[Image:1ny7.gif|left|200px]] |
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| - | '''COWPEA MOSAIC VIRUS (CPMV)''' | + | {{Structure |
| + | |PDB= 1ny7 |SIZE=350|CAPTION= <scene name='initialview01'>1ny7</scene>, resolution 3.00Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''COWPEA MOSAIC VIRUS (CPMV)''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1NY7 is a [ | + | 1NY7 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Cowpea_mosaic_virus Cowpea mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NY7 OCA]. |
==Reference== | ==Reference== | ||
| - | The refined crystal structure of cowpea mosaic virus at 2.8 A resolution., Lin T, Chen Z, Usha R, Stauffacher CV, Dai JB, Schmidt T, Johnson JE, Virology. 1999 Dec 5;265(1):20-34. PMID:[http:// | + | The refined crystal structure of cowpea mosaic virus at 2.8 A resolution., Lin T, Chen Z, Usha R, Stauffacher CV, Dai JB, Schmidt T, Johnson JE, Virology. 1999 Dec 5;265(1):20-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10603314 10603314] |
[[Category: Cowpea mosaic virus]] | [[Category: Cowpea mosaic virus]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: virus]] | [[Category: virus]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:03:14 2008'' |
Revision as of 11:03, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
COWPEA MOSAIC VIRUS (CPMV)
Overview
Comoviruses are a group of plant viruses in the picornavirus superfamily. The type member of comoviruses, cowpea mosaic virus (CPMV), was crystallized in the cubic space group I23, a = 317 A and the hexagonal space group P6(1)22, a = 451 A, c = 1038 A. Structures of three closely similar nucleoprotein particles were determined in the cubic form. The roughly 300-A capsid was similar to the picornavirus capsid displaying a pseudo T = 3 (P = 3) surface lattice. The three beta-sandwich domains adopt two orientations, one with the long axis radial and the other two with the long axes tangential in reference to the capsid sphere. T = 3 viruses display one or the other of these two orientations. The CPMV capsid was permeable to cesium ions, leading to a disturbance of the beta-annulus inside a channel-like structure, suggesting an ion channel. The hexagonal crystal form diffracted X rays to 3 A resolution, despite the large unit cell. The large ( approximately 200 A) solvent channels in the lattice allow exchange of CPMV cognate Fab fragments. As an initial step in the structure determination of the CPMV/Fab complex, the P6(1)22 crystal structure was solved by molecular replacement with the CPMV model determined in the cubic cell.
About this Structure
1NY7 is a Protein complex structure of sequences from Cowpea mosaic virus. Full crystallographic information is available from OCA.
Reference
The refined crystal structure of cowpea mosaic virus at 2.8 A resolution., Lin T, Chen Z, Usha R, Stauffacher CV, Dai JB, Schmidt T, Johnson JE, Virology. 1999 Dec 5;265(1):20-34. PMID:10603314
Page seeded by OCA on Thu Mar 20 13:03:14 2008
