2fyp
From Proteopedia
(Difference between revisions)
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| - | + | ==GRP94 in complex with the novel HSP90 Inhibitor Radester amine== | |
| - | + | <StructureSection load='2fyp' size='340' side='right' caption='[[2fyp]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2fyp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FYP FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RDE:2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL+5-CHLORO-2,4-DIHYDROXYBENZOATE'>RDE</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zwh|1zwh]], [[2fxs|2fxs]], [[1qy8|1qy8]], [[1u0z|1u0z]], [[2exl|2exl]], [[1yet|1yet]], [[1bgq|1bgq]], [[1osf|1osf]]</td></tr> | |
| - | + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 Canis lupus familiaris])</td></tr> | |
| - | == | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fyp RCSB], [http://www.ebi.ac.uk/pdbsum/2fyp PDBsum]</span></td></tr> |
| - | [[2fyp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYP OCA]. | + | <table> |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fy/2fyp_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Endoplasmin|Endoplasmin]] | *[[Endoplasmin|Endoplasmin]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Canis lupus familiaris]] | [[Category: Canis lupus familiaris]] | ||
[[Category: Gewirth, D T.]] | [[Category: Gewirth, D T.]] | ||
Revision as of 05:04, 29 September 2014
GRP94 in complex with the novel HSP90 Inhibitor Radester amine
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Categories: Canis lupus familiaris | Gewirth, D T. | Immormino, R M. | Chaperone | Geldanamycin | Grp94 | Hsp82 | Hsp90 | Htpg | Ligand | Radamide | Radester | Radicicol
