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Revision as of 20:50, 21 October 2012

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spinqualitylabelsall models PDB ID 1bzy Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1bzy, resolution 2.00Å ()
Ligands:	, ,
Activity:	Hypoxanthine phosphoribosyltransferase, with EC number 2.4.2.8
Structural annotation: Resources: CATH : 1Bzya00, 1Bzyb00, 1Bzyc00, 1Bzyd00 InterPro : Ipr005904, Ipr002375, Ipr000836 Pfam : PF00156 SCOP : d1bzya_, d1bzyb_, d1bzyc_, d1bzyd_ UniProt : P00492
Functional annotation: Cellular component: cytoplasm Biological process: purine nucleotide biosynthetic process purine ribonucleoside salvage nucleoside metabolic process hypoxanthine metabolic process protein homotetramerization behavior positive regulation of dopamine metabolic process Molecular function: transferase activity, transferring glycosyl groups hypoxanthine phosphoribosyltransferase activity protein binding protein homodimerization activity transferase activity magnesium ion binding metal ion binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR

Template:ABSTRACT PUBMED 10360366

About this Structure

1bzy is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Shi W, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC. The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor. Nat Struct Biol. 1999 Jun;6(6):588-93. PMID:10360366 doi:http://dx.doi.org/10.1038/9376