3j22

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'''Unreleased structure'''
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{{STRUCTURE_3j22| PDB=3j22 | SCENE= }}
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===The Enterovirus 71 A-particle===
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The entry 3j22 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/B2ZUN0_9ENTO B2ZUN0_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
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Authors: Shingler, K.S.
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==About this Structure==
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[[3j22]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi] and [http://en.wikipedia.org/wiki/Human_enterovirus_71 Human enterovirus 71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J22 OCA].
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Description: The Enterovirus 71 A-particle
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[[Category: Gekko coi]]
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[[Category: Human enterovirus 71]]
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[[Category: Shingler, K L.]]
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[[Category: 135]]
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[[Category: Ev71]]
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[[Category: Virus]]

Revision as of 01:38, 4 April 2013

Template:STRUCTURE 3j22

The Enterovirus 71 A-particle

Function

[B2ZUN0_9ENTO] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]

About this Structure

3j22 is a 3 chain structure with sequence from Gekko coi and Human enterovirus 71. Full crystallographic information is available from OCA.

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