4gzd

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'''Unreleased structure'''
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{{STRUCTURE_4gzd| PDB=4gzd | SCENE= }}
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===Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q===
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{{ABSTRACT_PUBMED_23553749}}
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The entry 4gzd is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/ENT2_YEAST ENT2_YEAST]] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.<ref>PMID:10449404</ref>
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Authors: Costakes, G.T., Stauffacher, C.V.
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==About this Structure==
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[[4gzd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZD OCA].
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Description: Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Costakes, G T.]]
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[[Category: Stauffacher, C V.]]
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[[Category: Endocytosis]]
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[[Category: Enth]]
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[[Category: Lipid binding protein]]

Revision as of 07:22, 16 May 2013

Template:STRUCTURE 4gzd

Contents

Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q

Template:ABSTRACT PUBMED 23553749

Function

[ENT2_YEAST] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.[1]

About this Structure

4gzd is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

  1. ↑ Wendland B, Steece KE, Emr SD. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J. 1999 Aug 16;18(16):4383-93. PMID:10449404 doi:10.1093/emboj/18.16.4383

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OCA

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