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4h11

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4h11| PDB=4h11 | SCENE= }}
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===Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy===
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{{ABSTRACT_PUBMED_23519667}}
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The entry 4h11 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DLG2_RAT DLG2_RAT]] Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).
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Authors: Fiorentini, M., Kastrup, J.S., Gajhede, M.
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==About this Structure==
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[[4h11]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H11 OCA].
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Description: Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy
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[[Category: Rattus norvegicus]]
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[[Category: Fiorentini, M.]]
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[[Category: Gajhede, M.]]
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[[Category: Kastrup, J S.]]
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[[Category: All beta pdz]]
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[[Category: Neuropeptide]]
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[[Category: Protein binding]]
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[[Category: Protein interaction]]

Revision as of 01:36, 4 April 2013

Template:STRUCTURE 4h11

Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy

Template:ABSTRACT PUBMED 23519667

Function

[DLG2_RAT] Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).

About this Structure

4h11 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

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OCA

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