1pgw
From Proteopedia
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| - | [[Image:1pgw.jpg|left|200px]] | + | [[Image:1pgw.jpg|left|200px]] |
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| - | '''BEAN POD MOTTLE VIRUS (BPMV), TOP COMPONENT''' | + | {{Structure |
| + | |PDB= 1pgw |SIZE=350|CAPTION= <scene name='initialview01'>1pgw</scene>, resolution 2.90Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''BEAN POD MOTTLE VIRUS (BPMV), TOP COMPONENT''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1PGW is a [ | + | 1PGW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bean_pod_mottle_virus Bean pod mottle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PGW OCA]. |
==Reference== | ==Reference== | ||
| - | Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus., Lin T, Cavarelli J, Johnson JE, Virology. 2003 Sep 15;314(1):26-33. PMID:[http:// | + | Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus., Lin T, Cavarelli J, Johnson JE, Virology. 2003 Sep 15;314(1):26-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14517057 14517057] |
[[Category: Bean pod mottle virus]] | [[Category: Bean pod mottle virus]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: virus]] | [[Category: virus]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:24:15 2008'' |
Revision as of 11:24, 20 March 2008
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| , resolution 2.90Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
BEAN POD MOTTLE VIRUS (BPMV), TOP COMPONENT
Overview
Ordered nucleic acid in an icosahedral virus was first visualized in the X-ray structure of the Picorna-like plant virus, Bean pod mottle virus (BPMV). Virus particles containing the 3500 nucleotide segment of the BPMV bipartite RNA genome (middle component) had nearly 20% of the genome ordered. Here we report the refined structures of the middle component, bottom component (particles containing the 5800 nucleotide segment of the genome), and top component (empty particles of BPMV capsid protein). The bottom component particles contain ordered RNA in the same location as middle component. Although the ordered RNA density in both nucleoprotein particles is the average of the contents of 60 icosahedral asymmetric units, both nucleoprotein components show that the base density for the first two nucleotides is predominantly purine, while the next five appear to be predominantly pyrimidine. The empty capsid demonstrates that RNA dictates the order of the N-terminal 19 residues of the large subunit because these residues are invisible in the top component.
About this Structure
1PGW is a Protein complex structure of sequences from Bean pod mottle virus. Full crystallographic information is available from OCA.
Reference
Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus., Lin T, Cavarelli J, Johnson JE, Virology. 2003 Sep 15;314(1):26-33. PMID:14517057
Page seeded by OCA on Thu Mar 20 13:24:15 2008
