1e5g

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m (Protected "1e5g" [edit=sysop:move=sysop])
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[[Image:1e5g.png|left|200px]]
 
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{{STRUCTURE_1e5g| PDB=1e5g | SCENE= }}
{{STRUCTURE_1e5g| PDB=1e5g | SCENE= }}
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===Solution structure of central CP module pair of a pox virus complement inhibitor===
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{{ABSTRACT_PUBMED_11243823}}
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===SOLUTION STRUCTURE OF CENTRAL CP MODULE PAIR OF A POX VIRUS COMPLEMENT INHIBITOR===
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==Function==
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[[http://www.uniprot.org/uniprot/VCP_VACCC VCP_VACCC]] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b.
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{{ABSTRACT_PUBMED_11243823}}
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==About this Structure==
==About this Structure==
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[[1e5g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA].
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[[1e5g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus_copenhagen Vaccinia virus copenhagen]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:011243823</ref><references group="xtra"/>
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<ref group="xtra">PMID:011243823</ref><references group="xtra"/><references/>
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[[Category: Vaccinia virus]]
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[[Category: Vaccinia virus copenhagen]]
[[Category: Barlow, P N.]]
[[Category: Barlow, P N.]]
[[Category: Bromek, K.]]
[[Category: Bromek, K.]]
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[[Category: Smith, B O.]]
[[Category: Smith, B O.]]
[[Category: Uhrin, D.]]
[[Category: Uhrin, D.]]
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[[Category: Complement]]
 
[[Category: Complement inhibitor]]
[[Category: Complement inhibitor]]
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[[Category: Module]]
 
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[[Category: Protein structure]]
 
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[[Category: Vaccinia virus]]
 

Revision as of 11:35, 3 July 2013

Template:STRUCTURE 1e5g

Contents

Solution structure of central CP module pair of a pox virus complement inhibitor

Template:ABSTRACT PUBMED 11243823

Function

[VCP_VACCC] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b.

About this Structure

1e5g is a 1 chain structure with sequence from Vaccinia virus copenhagen. Full experimental information is available from OCA.

Reference

  • Henderson CE, Bromek K, Mullin NP, Smith BO, Uhrin D, Barlow PN. Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein. J Mol Biol. 2001 Mar 16;307(1):323-39. PMID:11243823 doi:10.1006/jmbi.2000.4477

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