Neuroligin

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[[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic [[Neurexin]] (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4. The images at the left and at the right correspond to one representative NLGN, ''i.e.'' the crystal structure of human Neuroligin ([[3be8]]).
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[[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic [[Neurexin]] (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4.
For Structural Analysis of Neuroligin, See: [[Neuroligin-Neurexin Interaction]]
For Structural Analysis of Neuroligin, See: [[Neuroligin-Neurexin Interaction]]

Revision as of 10:04, 8 November 2012

Image:3be8a.png
Crystal Structure of human Neuroligin 3be8

Template:STRUCTURE 3b3q











Neuroligins (NLGN) are a family of postsynaptic proteins which bind to the presynaptic Neurexin (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4.

For Structural Analysis of Neuroligin, See: Neuroligin-Neurexin Interaction

Contents

3D Structures of Neuroligin

NLGN

3bl8 - mNLGN-2 cholinesterase domain – mouse
3be8 - hNLGN-4 cholinesterase domain – human
3bix - rNLGN-1 cholinesterase domain - rat


NLGN+NRXN

2xb6, 2wqz – hNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3b3q - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3biw - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain

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