1ef5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1ef5" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:1ef5.png|left|200px]]
+
==SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF RGL==
 +
<StructureSection load='1ef5' size='340' side='right' caption='[[1ef5]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1ef5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EF5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EF5 FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ef5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ef5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ef5 RCSB], [http://www.ebi.ac.uk/pdbsum/1ef5 PDBsum], [http://www.topsan.org/Proteins/RSGI/1ef5 TOPSAN]</span></td></tr>
 +
<table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ef/1ef5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The RGL protein, a homolog of the Ral GDP dissociation stimulator (RalGDS), has been identified as a downstream effector of Ras. In the present study, the solution structure of the Ras-binding domain of RGL (RGL-RBD) was determined by NMR spectroscopy. The overall fold of RGL-RBD consists of a five-stranded beta-sheet and two alpha-helices, which is the same topology as that of RalGDS-RBD. The backbone chemical shift perturbation of RGL-RBD upon interaction with the GTP analog-bound Ras was also examined. The solution structure of RGL-RBD, especially around some of the Ras-interacting residues, is appreciably different from that of RalGDS-RBD.
-
{{STRUCTURE_1ef5| PDB=1ef5 | SCENE= }}
+
Solution structure of the Ras-binding domain of RGL.,Kigawa T, Endo M, Ito Y, Shirouzu M, Kikuchi A, Yokoyama S FEBS Lett. 1998 Dec 28;441(3):413-8. PMID:9891982<ref>PMID:9891982</ref>
-
===SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF RGL===
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
[[1ef5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EF5 OCA].
+
__TOC__
-
 
+
</StructureSection>
-
==Reference==
+
-
<ref group="xtra">PMID:009891982</ref><references group="xtra"/>
+
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Endo, M.]]
[[Category: Endo, M.]]

Revision as of 11:28, 24 September 2014

SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF RGL

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ef5"
Views
Personal tools
Navigation
Toolbox