4g5y
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4g5y| PDB=4g5y | SCENE= }} | |
| + | ===Crystal Structure of Mycobacterium tuberculosis Pantothenate synthetase in a ternary complex with ATP and N,N-DIMETHYLTHIOPHENE-3-SULFONAMIDE=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4g5y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G5Y OCA]. | ||
| - | + | ==Reference== | |
| + | <references group="xtra"/><references/> | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Pantoate--beta-alanine ligase]] | ||
| + | [[Category: Abell, C.]] | ||
| + | [[Category: Blundell, T L.]] | ||
| + | [[Category: Ciulli, A.]] | ||
| + | [[Category: Silvestre, H L.]] | ||
| + | [[Category: Drug design]] | ||
| + | [[Category: Fragment-based]] | ||
| + | [[Category: Ligase]] | ||
| + | [[Category: Ligase-ligase inhibitor complex]] | ||
| + | [[Category: Pantothenate biosynthesis]] | ||
Revision as of 14:15, 3 July 2013
Contents |
Crystal Structure of Mycobacterium tuberculosis Pantothenate synthetase in a ternary complex with ATP and N,N-DIMETHYLTHIOPHENE-3-SULFONAMIDE
Function
[PANC_MYCTU] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.[1]
About this Structure
4g5y is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
