4hr9

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'''Unreleased structure'''
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{{STRUCTURE_4hr9| PDB=4hr9 | SCENE= }}
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===Human interleukin 17A===
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{{ABSTRACT_PUBMED_23695682}}
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The entry 4hr9 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN]] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
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Authors: Liu, S.
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==About this Structure==
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[[4hr9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HR9 OCA].
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Description: Human interleukin 17A
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==Reference==
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<ref group="xtra">PMID:023695682</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Liu, S.]]
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[[Category: Cytokine]]
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[[Category: Il17 receptor a and c]]
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[[Category: Immune response]]
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[[Category: Immune system]]

Revision as of 08:20, 19 June 2013

Template:STRUCTURE 4hr9

Contents

Human interleukin 17A

Template:ABSTRACT PUBMED 23695682

Function

[IL17_HUMAN] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

About this Structure

4hr9 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liu S, Song X, Chrunyk BA, Shanker S, Hoth LR, Marr ES, Griffor MC. Crystal structures of interleukin 17A and its complex with IL-17 receptor A. Nat Commun. 2013;4:1888. doi: 10.1038/ncomms2880. PMID:23695682 doi:10.1038/ncomms2880

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OCA

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