1e6i

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{{STRUCTURE_1e6i| PDB=1e6i | SCENE= }}
{{STRUCTURE_1e6i| PDB=1e6i | SCENE= }}
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===BROMODOMAIN FROM GCN5 COMPLEXED WITH ACETYLATED H4 PEPTIDE===
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===Bromodomain from GCN5 complexed with acetylated H4 peptide===
{{ABSTRACT_PUBMED_11080160}}
{{ABSTRACT_PUBMED_11080160}}
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[[Category: Owen, D J.]]
[[Category: Owen, D J.]]
[[Category: Travers, A A.]]
[[Category: Travers, A A.]]
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[[Category: Bromodomain]]
 
[[Category: Gene regulation]]
[[Category: Gene regulation]]
[[Category: Histone binding]]
[[Category: Histone binding]]
[[Category: N-acetyl lysine]]
[[Category: N-acetyl lysine]]

Revision as of 14:42, 28 November 2012

Template:STRUCTURE 1e6i

Bromodomain from GCN5 complexed with acetylated H4 peptide

Template:ABSTRACT PUBMED 11080160

About this Structure

1e6i is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Owen DJ, Ornaghi P, Yang JC, Lowe N, Evans PR, Ballario P, Neuhaus D, Filetici P, Travers AA. The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p. EMBO J. 2000 Nov 15;19(22):6141-9. PMID:11080160 doi:10.1093/emboj/19.22.6141
  • Shen W, Xu C, Huang W, Zhang J, Carlson JE, Tu X, Wu J, Shi Y. Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails. Biochemistry. 2007 Feb 27;46(8):2100-10. Epub 2007 Feb 3. PMID:17274598 doi:http://dx.doi.org/10.1021/bi0611208

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