Tryptase inhibitor

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 2: Line 2:
'''Tryptase inhibitors''' (TI) are used as anti-inflammatory agents in treating asthma and other airway inflammation diseases. Tryptase was found in elevated levels in various kinds of allergic inflammations.
'''Tryptase inhibitors''' (TI) are used as anti-inflammatory agents in treating asthma and other airway inflammation diseases. Tryptase was found in elevated levels in various kinds of allergic inflammations.
 +
</StructureSection>
==3D structures of tryptase inhibitor==
==3D structures of tryptase inhibitor==
 +
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
{{#tree:id=OrganizedByTopic|openlevels=0|
-
===Leech-derived tryptase inhibitor===
+
*Leech-derived tryptase inhibitor
-
[[1ldt]] – MlTI + trypsin – Medicinal leech<br />
+
**[[1ldt]] – MlTI + trypsin – Medicinal leech<br />
-
[[1an1]] - MlTI (mutant) + trypsin<br />
+
**[[1an1]] - MlTI (mutant) + trypsin<br />
-
[[2kmo]], [[2kmp]], [[2kmq]], [[2kmr]] – MlTI - NMR
+
**[[2kmo]], [[2kmp]], [[2kmq]], [[2kmr]] – MlTI - NMR
-
===Tick-derived tryptase inhibitor===
+
*Tick-derived tryptase inhibitor
-
[[2uux]] – tTI residues 44-96 – tick<br />
+
**[[2uux]] – tTI residues 44-96 – tick<br />
-
[[2uuy]] - tTI + trypsin<br />
+
**[[2uuy]] - tTI + trypsin<br />
-
[[2lfk]], [[2lfl]] – tTI - NMR
+
**[[2lfk]], [[2lfl]] – tTI - NMR
-
 
+
}}
-
</StructureSection>
+
[[Category: Topic Page]]

Revision as of 12:43, 15 December 2014

Structure of leech tryptase inhibitor (aqua) complex with trypsin (dark green) and Ca+2 ion (green) (PDB entry 1ldt)

Drag the structure with the mouse to rotate

3D structures of tryptase inhibitor

Updated on 15-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Personal tools