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2yoh

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'''Unreleased structure'''
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{{STRUCTURE_2yoh| PDB=2yoh | SCENE= }}
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===Plasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitor===
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{{ABSTRACT_PUBMED_23240776}}
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The entry 2yoh is ON HOLD until Paper Publication
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==About this Structure==
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[[2yoh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YOH OCA].
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Authors: Huaqing, C., Carrero-Lerida, J., Silva, A.P.G., Whittingham, J.L., Brannigan, J.A., Ruiz-Perez, L.M., Read, K.D., Wilson, K.S., Gonzalez-Pacanowska, D., Gilbert, I.H.
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==Reference==
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<ref group="xtra">PMID:023240776</ref><references group="xtra"/><references/>
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Description: Plasmodium falciparum thymidylate kinase in complex with a urea-alpha-deoxythymidine inhibitor
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[[Category: Plasmodium falciparum 3d7]]
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[[Category: DTMP kinase]]
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[[Category: Brannigan, J A.]]
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[[Category: Carrero-Lerida, J.]]
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[[Category: Gilbert, I H.]]
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[[Category: Gonzalez-Pacanowska, D.]]
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[[Category: Huaqing, C.]]
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[[Category: Read, K D.]]
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[[Category: Ruiz-Perez, L M.]]
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[[Category: Silva, A P.G.]]
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[[Category: Whittingham, J L.]]
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[[Category: Wilson, K S.]]
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[[Category: Inhibitor]]
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[[Category: Malaria]]
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[[Category: Transferase]]

Revision as of 12:57, 24 July 2013

Template:STRUCTURE 2yoh

Plasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitor

Template:ABSTRACT PUBMED 23240776

About this Structure

2yoh is a 2 chain structure with sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.

Reference

  • Cui H, Carrero-Lerida J, Silva AP, Whittingham JL, Brannigan JA, Ruiz-Perez LM, Read KD, Wilson KS, Gonzalez-Pacanowska D, Gilbert IH. Synthesis and evaluation of alpha-thymidine analogues as novel antimalarials. J Med Chem. 2012 Dec 27;55(24):10948-57. doi: 10.1021/jm301328h. Epub 2012 Dec, 14. PMID:23240776 doi:10.1021/jm301328h

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OCA

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