4h2a

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'''Unreleased structure'''
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{{STRUCTURE_4h2a| PDB=4h2a | SCENE= }}
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===Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)===
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The entry 4h2a is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN]] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
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Authors: Baker, P.J., Sorrell, F.J.
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==About this Structure==
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[[4h2a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H2A OCA].
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Description: Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)
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[[Category: Bacillus anthracis]]
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[[Category: Baker, P J.]]
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[[Category: Sorrell, F J.]]
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[[Category: Extracellular region]]
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[[Category: Metal ion binding]]
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[[Category: Protein binding]]
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[[Category: Toxin]]
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[[Category: Toxin delivery]]

Revision as of 08:17, 29 September 2013

Template:STRUCTURE 4h2a

Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)

Function

[PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.

About this Structure

4h2a is a 1 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

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OCA

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