1r3m
From Proteopedia
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| - | [[Image:1r3m.gif|left|200px]] | + | [[Image:1r3m.gif|left|200px]] |
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| - | '''Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease''' | + | {{Structure |
| + | |PDB= 1r3m |SIZE=350|CAPTION= <scene name='initialview01'>1r3m</scene>, resolution 2.2Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=PO4:PHOSPHATE ION'>PO4</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1R3M is a [ | + | 1R3M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R3M OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease., Berisio R, Sica F, De Lorenzo C, Di Fiore A, Piccoli R, Zagari A, Mazzarella L, FEBS Lett. 2003 Nov 6;554(1-2):105-10. PMID:[http:// | + | Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease., Berisio R, Sica F, De Lorenzo C, Di Fiore A, Piccoli R, Zagari A, Mazzarella L, FEBS Lett. 2003 Nov 6;554(1-2):105-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14596923 14596923] |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Pancreatic ribonuclease]] | [[Category: Pancreatic ribonuclease]] | ||
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[[Category: swapping]] | [[Category: swapping]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:46:23 2008'' |
Revision as of 11:46, 20 March 2008
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| , resolution 2.2Å | |||||||
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| Ligands: | |||||||
| Activity: | Pancreatic ribonuclease, with EC number 3.1.27.5 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease
Overview
Bovine seminal ribonuclease is a unique case of protein dimorphism, since it exists in two dimeric forms, with different biological and kinetic behavior, which interconvert into one another through three-dimensional swapping. Here we report the crystal structure, at 2.2 A resolution, of the unswapped form of bovine seminal ribonuclease. Besides completing the structural definition of bovine seminal ribonuclease conformational dimorphism, this study provides the structural basis to explain the dependence of the enzyme cooperative effects on its swapping state.
About this Structure
1R3M is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease., Berisio R, Sica F, De Lorenzo C, Di Fiore A, Piccoli R, Zagari A, Mazzarella L, FEBS Lett. 2003 Nov 6;554(1-2):105-10. PMID:14596923
Page seeded by OCA on Thu Mar 20 13:46:23 2008
