4ht6

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'''Unreleased structure'''
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{{STRUCTURE_4ht6| PDB=4ht6 | SCENE= }}
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===The Structure of a Yeast Dynein Dyn2-Pac11 Complex and Effect on Single Molecule Dynein Motor Activity===
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{{ABSTRACT_PUBMED_23761070}}
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The entry 4ht6 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DYL1_YEAST DYL1_YEAST]] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). [[http://www.uniprot.org/uniprot/PAC11_YEAST PAC11_YEAST]] Required for viability in the absence of the kinesin-related CIN8 mitotic motor. May be a dynein intermediate chain.
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Authors: Slep, K.C., Romes, E.R.
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==About this Structure==
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[[4ht6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HT6 OCA].
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Description: The Structure of a Yeast Dynein Dyn2-Pac11 Complex and Effect on Single Molecule Dynein Motor Activity
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==Reference==
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<ref group="xtra">PMID:023761070</ref><references group="xtra"/><references/>
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Romes, E R.]]
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[[Category: Slep, K C.]]
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[[Category: Dimerization]]
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[[Category: Dynein]]
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[[Category: Dynein intermediate chain dynein heavy chain]]
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[[Category: Intermediate chain]]
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[[Category: Light chain]]
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[[Category: Motor protein]]

Revision as of 04:11, 20 September 2013

Template:STRUCTURE 4ht6

Contents

The Structure of a Yeast Dynein Dyn2-Pac11 Complex and Effect on Single Molecule Dynein Motor Activity

Template:ABSTRACT PUBMED 23761070

Function

[DYL1_YEAST] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). [PAC11_YEAST] Required for viability in the absence of the kinesin-related CIN8 mitotic motor. May be a dynein intermediate chain.

About this Structure

4ht6 is a 6 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

  • Rao L, Romes EM, Nicholas MP, Brenner S, Tripathy A, Gennerich A, Slep KC. The yeast dynein Dyn2-Pac11 complex is a dynein dimerization/processivity factor: structural and single-molecule characterization. Mol Biol Cell. 2013 Aug;24(15):2362-2377. Epub 2013 Jun 12. PMID:23761070 doi:10.1091/mbc.E13-03-0166

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OCA

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