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1k4w

From Proteopedia

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[[Image:1k4w.png|left|200px]]
 
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{{STRUCTURE_1k4w| PDB=1k4w | SCENE= }}
{{STRUCTURE_1k4w| PDB=1k4w | SCENE= }}
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===X-ray structure of the orphan nuclear receptor ROR beta ligand-binding domain in the active conformation===
===X-ray structure of the orphan nuclear receptor ROR beta ligand-binding domain in the active conformation===
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{{ABSTRACT_PUBMED_11689423}}
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{{ABSTRACT_PUBMED_11689423}}
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==Function==
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[[http://www.uniprot.org/uniprot/RORB_RAT RORB_RAT]] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:011689423</ref><references group="xtra"/>
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<ref group="xtra">PMID:011689423</ref><references group="xtra"/><references/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Greiner, E.]]
[[Category: Greiner, E.]]

Revision as of 18:53, 24 March 2013

Template:STRUCTURE 1k4w

Contents

X-ray structure of the orphan nuclear receptor ROR beta ligand-binding domain in the active conformation

Template:ABSTRACT PUBMED 11689423

Function

[RORB_RAT] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.

About this Structure

1k4w is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Stehlin C, Wurtz JM, Steinmetz A, Greiner E, Schule R, Moras D, Renaud JP. X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation. EMBO J. 2001 Nov 1;20(21):5822-31. PMID:11689423 doi:10.1093/emboj/20.21.5822

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OCA

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