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1lgn
From Proteopedia
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| - | [[Image:1lgn.png|left|200px]] | ||
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{{STRUCTURE_1lgn| PDB=1lgn | SCENE= }} | {{STRUCTURE_1lgn| PDB=1lgn | SCENE= }} | ||
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===DECAMERIC DAMP COMPLEX OF HUMAN SERUM AMYLOID P COMPONENT=== | ===DECAMERIC DAMP COMPLEX OF HUMAN SERUM AMYLOID P COMPONENT=== | ||
| + | {{ABSTRACT_PUBMED_9217261}} | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:009217261</ref><references group="xtra"/> | + | <ref group="xtra">PMID:009217261</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hohenester, E.]] | [[Category: Hohenester, E.]] | ||
Revision as of 21:22, 24 March 2013
Contents |
DECAMERIC DAMP COMPLEX OF HUMAN SERUM AMYLOID P COMPONENT
Template:ABSTRACT PUBMED 9217261
Disease
[SAMP_HUMAN] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
Function
[SAMP_HUMAN] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
About this Structure
1lgn is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hohenester E, Hutchinson WL, Pepys MB, Wood SP. Crystal structure of a decameric complex of human serum amyloid P component with bound dAMP. J Mol Biol. 1997 Jun 20;269(4):570-8. PMID:9217261 doi:10.1006/jmbi.1997.1075
