1n1j

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[[Image:1n1j.png|left|200px]]
 
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{{STRUCTURE_1n1j| PDB=1n1j | SCENE= }}
{{STRUCTURE_1n1j| PDB=1n1j | SCENE= }}
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===Crystal structure of the NF-YB/NF-YC histone pair===
===Crystal structure of the NF-YB/NF-YC histone pair===
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{{ABSTRACT_PUBMED_12401788}}
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{{ABSTRACT_PUBMED_12401788}}
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==Function==
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[[http://www.uniprot.org/uniprot/NFYB_HUMAN NFYB_HUMAN]] Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. [[http://www.uniprot.org/uniprot/NFYC_HUMAN NFYC_HUMAN]] Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.
==About this Structure==
==About this Structure==
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[[1n1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1J OCA].
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[[1n1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1J OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:012401788</ref><references group="xtra"/>
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<ref group="xtra">PMID:012401788</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Cocchiarella, F.]]
[[Category: Cocchiarella, F.]]
[[Category: Mantovani, R.]]
[[Category: Mantovani, R.]]

Revision as of 07:55, 16 April 2014

Template:STRUCTURE 1n1j

Contents

Crystal structure of the NF-YB/NF-YC histone pair

Template:ABSTRACT PUBMED 12401788

Function

[NFYB_HUMAN] Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. [NFYC_HUMAN] Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.

About this Structure

1n1j is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Romier C, Cocchiarella F, Mantovani R, Moras D. The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y. J Biol Chem. 2003 Jan 10;278(2):1336-45. Epub 2002 Oct 24. PMID:12401788 doi:10.1074/jbc.M209635200

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