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1mim

From Proteopedia

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[[Image:1mim.png|left|200px]]
 
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{{STRUCTURE_1mim| PDB=1mim | SCENE= }}
{{STRUCTURE_1mim| PDB=1mim | SCENE= }}
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===IGG FAB FRAGMENT (CD25-BINDING)===
===IGG FAB FRAGMENT (CD25-BINDING)===
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{{ABSTRACT_PUBMED_15299676}}
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{{ABSTRACT_PUBMED_15299676}}
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==Disease==
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[[http://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN]] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[http://omim.org/entry/614102 614102]]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref>
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:015299676</ref><references group="xtra"/>
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<ref group="xtra">PMID:015299676</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mikol, V.]]
[[Category: Mikol, V.]]
[[Category: C region]]
[[Category: C region]]
[[Category: Immunoglobulin]]
[[Category: Immunoglobulin]]

Revision as of 07:13, 25 March 2013

Template:STRUCTURE 1mim

Contents

IGG FAB FRAGMENT (CD25-BINDING)

Template:ABSTRACT PUBMED 15299676

Disease

[IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.[1]

About this Structure

1mim is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mikol V. Structure of the fab fragment of SDZ CHI621: a chimeric antibody against CD25. Acta Crystallogr D Biol Crystallogr. 1996 May 1;52(Pt 3):534-42. PMID:15299676 doi:10.1107/S0907444996000704
  1. ↑ Stavnezer-Nordgren J, Kekish O, Zegers BJ. Molecular defects in a human immunoglobulin kappa chain deficiency. Science. 1985 Oct 25;230(4724):458-61. PMID:3931219

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