6-phosphogluconate dehydrogenase
From Proteopedia
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[[2p4q]] - 6PDH – yeast<BR /> | [[2p4q]] - 6PDH – yeast<BR /> | ||
[[2zyg]] - 6PDH (mutant) – ''Klebsiella pneumonia''<BR /> | [[2zyg]] - 6PDH (mutant) – ''Klebsiella pneumonia''<BR /> | ||
| - | [[4e21]] - | + | [[4e21]] - Gm6PDH – ''Geobacter metallireducens'' |
| + | [[4gbj]] – Df6PDH – ''Dyadobacter fermentans''<br /> | ||
| + | [[4gwg]] - h6PDH – human<br /> | ||
'''6PDH binary complex''' | '''6PDH binary complex''' | ||
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[[1pgp]] - s6PDH + 6PG<BR /> | [[1pgp]] - s6PDH + 6PG<BR /> | ||
[[1pgq]] - s6PDH + AMP<BR /> | [[1pgq]] - s6PDH + AMP<BR /> | ||
| - | [[2jkv]] - | + | [[2jkv]] - h6PDH + NADP <BR /> |
| + | [[4gwk]] - h6PDH + 3PG<br /> | ||
[[2zya]] - Ec6PDH (mutant) + 6PG – ''Escherichia coli''<BR /> | [[2zya]] - Ec6PDH (mutant) + 6PG – ''Escherichia coli''<BR /> | ||
[[2w8z]], [[2w90]] - 6PDH + 6PG – ''Geobacillus stearothermophilus''<BR /> | [[2w8z]], [[2w90]] - 6PDH + 6PG – ''Geobacillus stearothermophilus''<BR /> | ||
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[[2iz1]] - Ll6PDH + inhibitor + ADP <BR /> | [[2iz1]] - Ll6PDH + inhibitor + ADP <BR /> | ||
| - | [[3fwn]] - Ec6PDH (mutant) + ADP + 6PG | + | [[3fwn]] - Ec6PDH (mutant) + ADP + 6PG<br /> |
| + | [[3pef]] – Gm6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose<br /> | ||
| + | [[3w6u]] – Pc6PDH + NADP + monophosphoadenosine diphosphoribose – ''Pyrobaculum calidifontis''<br /> | ||
| + | [[3w6z]] – Pc6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose <br /> | ||
'''6PDH quaternary complex''' | '''6PDH quaternary complex''' | ||
Revision as of 11:47, 21 January 2014
Template:STRUCTURE 1pgj 6-phosphogluconate dehydrogenase (6PDH) catalyzes the decarboxylation reduction of 6-phosphogluconate (6PG) to ribulose 5-phosphate and CO2. This reaction is part of the pentose phosphate pathway. NADP is a cofactor in this reaction and is converted to NADPH.
3D structures of 6-phosphogluconate dehydrogenase
2pgd - s6PDH – sheep
1pgj - 6PDH – Trypanosoma brucei
2p4q - 6PDH – yeast
2zyg - 6PDH (mutant) – Klebsiella pneumonia
4e21 - Gm6PDH – Geobacter metallireducens
4gbj – Df6PDH – Dyadobacter fermentans
4gwg - h6PDH – human
6PDH binary complex
1pgn – s6PDH + Br-NADP
1pgo - s6PDH + NADP
1pgp - s6PDH + 6PG
1pgq - s6PDH + AMP
2jkv - h6PDH + NADP
4gwk - h6PDH + 3PG
2zya - Ec6PDH (mutant) + 6PG – Escherichia coli
2w8z, 2w90 - 6PDH + 6PG – Geobacillus stearothermophilus
2iyo - Ll6PDH + 6PG – Lactococcus lactis
2zyd - Ec6PDH (mutant) + glucose
6PDH ternary complex
2iz1 - Ll6PDH + inhibitor + ADP
3fwn - Ec6PDH (mutant) + ADP + 6PG
3pef – Gm6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose
3w6u – Pc6PDH + NADP + monophosphoadenosine diphosphoribose – Pyrobaculum calidifontis
3w6z – Pc6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose
6PDH quaternary complex
2iyp - Ll6PDH + ADP + ribulose 5-phosphate + NADP
2iz0 - Ll6PDH + inhibitor + ADP + NADP
