Caspase-3 Regulatory Mechanisms
From Proteopedia
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== Introduction == | == Introduction == | ||
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| + | Caspases are '''c'''ysteine-dependent '''asp'''artate prote'''ases''' and are the key facilitators of apoptosis or programmed cell death. Apoptosis is tightly regulated by these caspases, and dysregulation of caspase functions have been implicated in wide variety of diseases such as neurodegeneration, cancer, heart disease and some metabolic disorders. | ||
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== Regulation of Caspase-3== | == Regulation of Caspase-3== | ||
<StructureSection load='1dq8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1dq8]])' scene=''> | <StructureSection load='1dq8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1dq8]])' scene=''> | ||
Revision as of 13:02, 12 December 2012
Introduction
Caspases are cysteine-dependent aspartate proteases and are the key facilitators of apoptosis or programmed cell death. Apoptosis is tightly regulated by these caspases, and dysregulation of caspase functions have been implicated in wide variety of diseases such as neurodegeneration, cancer, heart disease and some metabolic disorders.
Regulation of Caspase-3
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Proteopedia Page Contributors and Editors (what is this?)
Scott Eron, Banyuhay P. Serrano, Alexander Berchansky, Yunlong Zhao, Jaime Prilusky, Michal Harel
