Sandox Bay Serrano
From Proteopedia
(Difference between revisions)
| Line 6: | Line 6: | ||
| - | + | ||
<StructureSection load='2h5i_mm1-1.pdb' size='350' side='right' caption='Caspase-3 dimer (PDB entry [[2h5i]])' scene=''> | <StructureSection load='2h5i_mm1-1.pdb' size='350' side='right' caption='Caspase-3 dimer (PDB entry [[2h5i]])' scene=''> | ||
Revision as of 16:46, 12 December 2012
Introduction
Caspase-3 Structure
Caspases are synthesized in the cell in their zymogen forms, consisting of an N-terminal prodomain followed by a large and a small subunit linked to each other by an intersubunit linker. As an executioner caspase, caspase-3 has a short N-terminal prodomain and like any other caspases, cleavage of the intersubunit linker at a specific aspartate residue generates the mature form of the enzyme.
| |||||||||||
