Sandox Bay Serrano

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== Introduction ==
== Introduction ==
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Caspases are '''c'''ysteine-'''asp'''artic acid prote'''ases''' and are key protein facilitators for the faithful execution of apoptosis or programmed cell death. Because of the crucial role of caspases in the the apoptotic pathway, any dysregulation in their functions would be deleterious to the cell.
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Caspases are '''c'''ysteine-'''asp'''artic acid prote'''ases''' and are key protein facilitators for the faithful execution of apoptosis or programmed cell death. Dysregulation in the apoptotic pathway has been implicated in a variety of diseases such as neurodegeneration, cancer, heart disease and some metabolic disorders. Because of the crucial role of caspases in the the apoptotic pathway, abnormalities in their functions would cause a haywire in the apoptotic pathway and can be deleterious to the cell. Caspases are thus being considered as therapeutic targets in apoptosis-related diseases.
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Caspase-3 has been particularly

Revision as of 19:28, 12 December 2012

Introduction

Caspases are cysteine-aspartic acid proteases and are key protein facilitators for the faithful execution of apoptosis or programmed cell death. Dysregulation in the apoptotic pathway has been implicated in a variety of diseases such as neurodegeneration, cancer, heart disease and some metabolic disorders. Because of the crucial role of caspases in the the apoptotic pathway, abnormalities in their functions would cause a haywire in the apoptotic pathway and can be deleterious to the cell. Caspases are thus being considered as therapeutic targets in apoptosis-related diseases.

Caspase-3 has been particularly


</StructureSection>

Caspase-3 dimer (PDB entry 2h5i)

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Proteopedia Page Contributors and Editors (what is this?)

Banyuhay P. Serrano, Michal Harel

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