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2lkq
From Proteopedia
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{{STRUCTURE_2lkq| PDB=2lkq | SCENE= }} | {{STRUCTURE_2lkq| PDB=2lkq | SCENE= }} | ||
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===NMR structure of the lambda 5 22-45 peptide=== | ===NMR structure of the lambda 5 22-45 peptide=== | ||
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{{ABSTRACT_PUBMED_23124203}} | {{ABSTRACT_PUBMED_23124203}} | ||
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| + | ==Disease== | ||
| + | [[http://www.uniprot.org/uniprot/IGLL1_HUMAN IGLL1_HUMAN]] Defects in IGLL1 are the cause of agammaglobulinemia type 2 (AGM2) [MIM:[http://omim.org/entry/613500 613500]]. It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/IGLL1_HUMAN IGLL1_HUMAN]] Critical for B-cell development.<ref>PMID:9419212</ref> | ||
==About this Structure== | ==About this Structure== | ||
[[2lkq]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LKQ OCA]. | [[2lkq]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LKQ OCA]. | ||
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| + | ==Reference== | ||
| + | <references group="xtra"/><references/> | ||
[[Category: Boned, A.]] | [[Category: Boned, A.]] | ||
[[Category: Bornet, O.]] | [[Category: Bornet, O.]] | ||
Revision as of 23:38, 24 March 2013
Contents |
NMR structure of the lambda 5 22-45 peptide
Template:ABSTRACT PUBMED 23124203
Disease
[IGLL1_HUMAN] Defects in IGLL1 are the cause of agammaglobulinemia type 2 (AGM2) [MIM:613500]. It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life.
Function
[IGLL1_HUMAN] Critical for B-cell development.[1]
About this Structure
2lkq is a 1 chain structure. Full experimental information is available from OCA.
