Hormone

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[[Beta-2 Adrenergic Receptor]]<br />
[[Beta-2 Adrenergic Receptor]]<br />
The human β2 adrenergic receptor bound to a G-protein ([[3sn6]]) and [[hormone]] analog is featured in an image on the right, and additional structures are on the [[Adrenergic receptor|Adrenergic receptor page]]. <br />
The human β2 adrenergic receptor bound to a G-protein ([[3sn6]]) and [[hormone]] analog is featured in an image on the right, and additional structures are on the [[Adrenergic receptor|Adrenergic receptor page]]. <br />
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{{Template:GPCR3sn6}}
===Angiotensinogen===
===Angiotensinogen===
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[[1hcn]] - Chorionic Gonadotropin – human<br />
[[1hcn]] - Chorionic Gonadotropin – human<br />
[[1hd4]] - Alpha-subunit of Chorionic Gonadotropin – human<br />
[[1hd4]] - Alpha-subunit of Chorionic Gonadotropin – human<br />
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===Estrogen-related receptor===
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Estrogen-related recepto – human and others, see [[Estrogen-related_receptor#3D_structures_of_estrogen-related_receptor|Estrogen-related receptor structures]]<br />
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===Farnesoid X Receptor ===
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[[3olf]], [[3omk]], [[3omm]], [[3oof]], [[3ook]], [[3okh]], [[3oki]] - Farnesoid X Receptor – human<br />
===Follicle-Stimulating Hormone===
===Follicle-Stimulating Hormone===
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[[2xn3]], [[2xn5]], [[2xn6]], [[2xn7]] - Thyroxine-binding Globulin – human<br />
[[2xn3]], [[2xn5]], [[2xn6]], [[2xn7]] - Thyroxine-binding Globulin – human<br />
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===Farnesoid X Receptor ===
 
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[[3olf]], [[3omk]], [[3omm]], [[3oof]], [[3ook]], [[3okh]], [[3oki]] - Farnesoid X Receptor – human<br />
 
===PACAP/glucagon family of peptide hormones===
===PACAP/glucagon family of peptide hormones===
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[[2jod]] - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular domain of the human splice variant hPAC1-RS determined by NMR - human<br />
[[2jod]] - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular domain of the human splice variant hPAC1-RS determined by NMR - human<br />
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===Estrogen-related receptor===
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Estrogen-related recepto – human and others, see [[Estrogen-related_receptor#3D_structures_of_estrogen-related_receptor|Estrogen-related receptor structures]]<br />
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Revision as of 23:52, 15 December 2012

In the field of modern endocrinology, a hormone is any substance, generated either externally or internally, that operates via a receptor at the cellular level, which conveys to to the cell a message to stop, start, or modulate a cellular process.

Contents

Guide to Proteopedia Pages Concerning Hormones and their Receptors

Articles in Proteopedia concerning Hormone include:


To view automatically seeded indices concerning Hormone, see:


Additional 3D Structures of Hormones and Hormone Receptors and Related Molecules

Adrenaline

Beta-2 Adrenergic Receptor
The human β2 adrenergic receptor bound to a G-protein (3sn6) and hormone analog is featured in an image on the right, and additional structures are on the Adrenergic receptor page.

 

Drag the structure with the mouse to rotate
An activated G protein-coupled receptor (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) (3sn6), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green.



Angiotensinogen

2wxw, 2wxx, 2wxy, 2wxz, 2wy0, 2wy1, 2x0b - Angiotensinogen – human, rat, mouse

Chorionic Gonadotropin

1hrp - Chorionic Gonadotropin – human
1hcn - Chorionic Gonadotropin – human
1hd4 - Alpha-subunit of Chorionic Gonadotropin – human

Estrogen-related receptor

Estrogen-related recepto – human and others, see Estrogen-related receptor structures

Farnesoid X Receptor

3olf, 3omk, 3omm, 3oof, 3ook, 3okh, 3oki - Farnesoid X Receptor – human

Follicle-Stimulating Hormone

Drag the structure with the mouse to rotate
FSH binding to the leucine-rich domain of Follicle Stimulating Hormone Receptor (1fl7 morphing to 1xwd, resolution 2.92Å)


1fl7 - Follicle-Stimulating Hormone – human
1xwd - Human Follicle Stimulating Hormone complexed with its Receptor – human

Glucocorticoid

3mne, 3mno, 3mnp - Glucocorticoid Receptor Ligand-binding Domain – human

Glucose-dependent Insulinotropic Polypeptide

Glucose-dependent Insulinotropic Polypeptide Receptor

Growth Hormone

3hhr - Growth Hormone complexed with the extracellular portion of its receptor - human
1hwh - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human
1bp3 - Growth Hormone complexed with the prolactin receptor - human
3mjg, 3mjk - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex – human
Vascular Endothelial Growth Factor – human and others, see Vascular Endothelial Growth Factor Structures
Vascular Endothelial Growth Factor Receptor – human, see Vascular Endothelial Growth Factor Receptor Structures
2xdg - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human

Insulin

3ir0 , 1mso , 1trz , 2qiu , 2r34, 2r35 , 2r36, 3ilg, 2kjj , 2kju - Insulin – human
3nw5, 3nw6, 3nw7 - insulin-like growth factor 1 receptor – human
3loh, 2dtg - insulin receptor ectodomain – human
Glucose-dependent Insulinotropic Polypeptide Receptor

Progesterone

3hq5,3g8n, 3g8o, 3hq5 - Progesterone – human

Thyroid-Stimulating hormone

3g04 - TSH receptor in complex with a thyroid-stimulating autoantibody – human

Thyroid hormone

2nll - DNA-Binding domain in complex with an inverted repeat class of thyroid response element– rat
1xzx

Thyroxine

2xn3, 2xn5, 2xn6, 2xn7 - Thyroxine-binding Globulin – human


PACAP/glucagon family of peptide hormones

3n94 - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure 2jod and vice versa
2jod - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular domain of the human splice variant hPAC1-RS determined by NMR - human



ADD 3dzu

See Also


External Resources

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