This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4gk6
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | ==X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from Mycobacterium abscessus== | |
| - | + | <StructureSection load='4gk6' size='340' side='right' caption='[[4gk6]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4gk6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_abscessus_atcc_19977 Mycobacterium abscessus atcc 19977]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GK6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GK6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dut, MAB_3003c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=561007 Mycobacterium abscessus ATCC 19977])</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gk6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gk6 RCSB], [http://www.ebi.ac.uk/pdbsum/4gk6 PDBsum]</span></td></tr> |
| - | [[4gk6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_abscessus_atcc_19977 Mycobacterium abscessus atcc 19977]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GK6 OCA]. | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/B1MCW0_MYCA9 B1MCW0_MYCA9]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116][SAAS:SAAS00071014] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Mycobacterium abscessus atcc 19977]] | [[Category: Mycobacterium abscessus atcc 19977]] | ||
[[Category: DUTP diphosphatase]] | [[Category: DUTP diphosphatase]] | ||
| - | [[Category: | + | [[Category: Structural genomic]] |
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: National institute of allergy and infectious disease]] | [[Category: National institute of allergy and infectious disease]] | ||
[[Category: Niaid]] | [[Category: Niaid]] | ||
| - | [[Category: Seattle structural genomics center for infectious disease]] | ||
[[Category: Ssgcid]] | [[Category: Ssgcid]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 21:05, 25 December 2014
X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from Mycobacterium abscessus
| |||||||||||
