1sry
From Proteopedia
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| - | [[Image:1sry.gif|left|200px]] | + | [[Image:1sry.gif|left|200px]] |
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| - | '''REFINED CRYSTAL STRUCTURE OF THE SERYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION''' | + | {{Structure |
| + | |PDB= 1sry |SIZE=350|CAPTION= <scene name='initialview01'>1sry</scene>, resolution 2.5Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Serine--tRNA_ligase Serine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.11 6.1.1.11] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''REFINED CRYSTAL STRUCTURE OF THE SERYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1SRY is a [ | + | 1SRY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SRY OCA]. |
==Reference== | ==Reference== | ||
| - | Refined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolution., Fujinaga M, Berthet-Colominas C, Yaremchuk AD, Tukalo MA, Cusack S, J Mol Biol. 1993 Nov 5;234(1):222-33. PMID:[http:// | + | Refined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolution., Fujinaga M, Berthet-Colominas C, Yaremchuk AD, Tukalo MA, Cusack S, J Mol Biol. 1993 Nov 5;234(1):222-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8230201 8230201] |
[[Category: Serine--tRNA ligase]] | [[Category: Serine--tRNA ligase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: ligase(synthetase)]] | [[Category: ligase(synthetase)]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:08:53 2008'' |
Revision as of 12:08, 20 March 2008
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| , resolution 2.5Å | |||||||
|---|---|---|---|---|---|---|---|
| Activity: | Serine--tRNA ligase, with EC number 6.1.1.11 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
REFINED CRYSTAL STRUCTURE OF THE SERYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION
Overview
The three-dimensional structure of the seryl-tRNA synthetase from Thermus thermophilus has been determined and refined at 2.5 A resolution. The final model consists of a dimer of 421 residues each and 190 water molecules. The R-factor is 18.4% for all the data between 10 and 2.5 A resolution. The structure is very similar to that of the homologous enzyme from Escherichia coli, with an r.m.s. difference of 1.5 A for the 357 alpha-carbon atoms considered equivalent. The comparison of the two structures indicates increased hydrophobicity, reduced conformational entropy and reduced torsional strain as possible mechanisms by which thermostability is obtained in the enzyme from the thermophile.
About this Structure
1SRY is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.
Reference
Refined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolution., Fujinaga M, Berthet-Colominas C, Yaremchuk AD, Tukalo MA, Cusack S, J Mol Biol. 1993 Nov 5;234(1):222-33. PMID:8230201
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