Sandbox UC 10

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== N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN ==
== N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN ==
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Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane.
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<StructureSection load='1dxx' size='350' side='right' caption='Structure N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN (PDB entry [[1dxx]])' scene=''>
<StructureSection load='1dxx' size='350' side='right' caption='Structure N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN (PDB entry [[1dxx]])' scene=''>
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Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane.
 
[[Image:1dxx.png|left|200px|thumb|Crystal Structure of Human dystrophin, [[1dxx]]]]
[[Image:1dxx.png|left|200px|thumb|Crystal Structure of Human dystrophin, [[1dxx]]]]
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[[Image:imag1gonzalo.jpg|right|200px|thumb|Comparacion de la degeneracion muscular, [[1dxx]]]]
[[Image:imag1gonzalo.jpg|right|200px|thumb|Comparacion de la degeneracion muscular, [[1dxx]]]]
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[[Image:MW_Folding_Simulations.gif|center|200px|thumb|[[1dxx]]]]
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[[Image:MW_Folding_Simulations.gif|center|200px|thumb|[[1dxx]]]]
 
<scene name='Sandbox_UC_10/Scene1/1'>Rainbow</scene>
<scene name='Sandbox_UC_10/Scene1/1'>Rainbow</scene>

Revision as of 19:34, 19 December 2012

N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN

Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane.

Structure N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN (PDB entry 1dxx)

Drag the structure with the mouse to rotate

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Ref1[1] Ref2 [2]

  1. Nadeau D, Marchand C. Change in the kinetics of sulphacetamide tissue distribution in Walker tumor-bearing rats. Drug Metab Dispos. 1975 Nov-Dec;3(6):565-76. PMID:1234
  2. Rubinstein MH. A new granulation method for compressed tablets [proceedings]. J Pharm Pharmacol. 1976 Dec;28 Suppl:67P. PMID:12345
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