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Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane. | Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane. | ||
+ | [[Image:1dxx.png|200px|thumb|Crystal Structure of Human dystrophin, [[1dxx]]]] | ||
+ | [[Image:imag1gonzalo.jpg|200px|thumb|Comparacion de la degeneracion muscular, [[1dxx]]]] | ||
+ | |||
+ | [[Image:MW_Folding_Simulations.gif|200px|thumb|[[1dxx]]]] | ||
{{STRUCTURE_1dxx| PDB=1dxx | SIZE=400| SCENE= |right|CAPTION=N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN [[3fsp]] }} | {{STRUCTURE_1dxx| PDB=1dxx | SIZE=400| SCENE= |right|CAPTION=N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN [[3fsp]] }} | ||
+ | <scene name='1xjo/Active_site/3'>active site</scene> | ||
- | [[Image:1dxx.png|200px|thumb|Crystal Structure of Human dystrophin, [[1dxx]]]] | ||
- | |||
- | [[Image:imag1gonzalo.jpg|200px|thumb|Comparacion de la degeneracion muscular, [[1dxx]]]] | ||
- | |||
- | [[Image:MW_Folding_Simulations.gif|200px|thumb|[[1dxx]]]] | ||
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Revision as of 20:05, 19 December 2012
N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN
Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane.

Crystal Structure of Human dystrophin, 1dxx

Comparacion de la degeneracion muscular, 1dxx
Amino Terminus | Carboxy Terminus |
- ↑ Nadeau D, Marchand C. Change in the kinetics of sulphacetamide tissue distribution in Walker tumor-bearing rats. Drug Metab Dispos. 1975 Nov-Dec;3(6):565-76. PMID:1234
- ↑ Rubinstein MH. A new granulation method for compressed tablets [proceedings]. J Pharm Pharmacol. 1976 Dec;28 Suppl:67P. PMID:12345