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== N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN ==
== N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN ==
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<StructureSection load='1dq8' size='500' side='right' caption='N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN (PDB entry [[1dxx]])' scene=''>Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane.<scene name='1xjo/Active_site/3'>active site</scene>
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<StructureSection load='1dq8' size='500' side='right' caption='N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN (PDB entry [[1dxx]])' scene=''>[[Image:1dxx.png|200px|left|thumb|Crystal Structure of Human dystrophin, [[1dxx]]]]Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane.<scene name='1xjo/Active_site/3'>active site</scene>
[[Image:1dxx.png|200px|center|thumb|Crystal Structure of Human dystrophin, [[1dxx]]]]
[[Image:1dxx.png|200px|center|thumb|Crystal Structure of Human dystrophin, [[1dxx]]]]

Revision as of 20:19, 19 December 2012

N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN

N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN (PDB entry 1dxx)

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QUIZ TIME !!

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quizás.

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Referencias

Ref1[2] Ref2 [3]

  1. ↑ Norwood FL, Sutherland-Smith AJ, Keep NH, Kendrick-Jones J. The structure of the N-terminal actin-binding domain of human dystrophin and how mutations in this domain may cause Duchenne or Becker muscular dystrophy. Structure. 2000 May 15;8(5):481-91. PMID:10801490
  2. ↑ Nadeau D, Marchand C. Change in the kinetics of sulphacetamide tissue distribution in Walker tumor-bearing rats. Drug Metab Dispos. 1975 Nov-Dec;3(6):565-76. PMID:1234
  3. ↑ Rubinstein MH. A new granulation method for compressed tablets [proceedings]. J Pharm Pharmacol. 1976 Dec;28 Suppl:67P. PMID:12345
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