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<Structure load='1L6J' size='350' frame='true' align='right' caption='MMP-9 (from PDB entry 1L6J)' scene='scene 1' />

Revision as of 00:30, 11 December 2014

MMP9

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MMP9 is a member of matrix metalloproteinases (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of have been designed to bind to the and inhibit the activity of MMP9.


MMP-9 (from PDB entry 1L6J)

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Reference: Siân Rowsell, Paul Hawtin,Claire A. Minshull, Holly Jepson, Sarah M.V. Brockbank,Derek G. Barratt, Anthony M. Slater, William L. McPheat, David Waterson, Adriano M. Henney, Richard A. Pauptit Crystal Structure of Human MMP9 in Complex with a Reverse Hydroxamate Inhibitor, Volume 319, Issue 1, 24 May 2002, Pages 173–181


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Jiaming Zhuang, Mallory Gordon

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