Isopenicillin N synthase

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==3D structures of isopenicillin N synthase==
==3D structures of isopenicillin N synthase==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Fe containing IPNS===
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*Fe containing IPNS
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[[1bk0]] - AnIPNS + ACV – ''Aspergillus nidulans''<br />
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**[[1bk0]] - AnIPNS + ACV – ''Aspergillus nidulans''<br />
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[[2bjs]] - AnIPNS (mutant) + ACV<br />
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**[[2bjs]] - AnIPNS (mutant) + ACV<br />
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[[1qiq]], [[1qjf]], [[1hb1]], [[1hb2]], [[1hb3]], [[1hb4]], [[1odm]], [[1odn]], [[1oc1]], [[1uzw]], [[1w03]], [[1w05]], [[2bu9]], [[1w3v]], [[1w3x]], [[2ivi]], [[2ivj]], [[2vau]], [[2vbb]], [[2vbd]], [[2vbp]], [[2vcm]], [[2ve1]], [[2wo7]], [[2y6f]], [[2y60]], [[2y86]] - AnIPNS + ACV derivative<br />
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**[[1qiq]], [[1qjf]], [[1hb1]], [[1hb2]], [[1hb3]], [[1hb4]], [[1odm]], [[1odn]], [[1oc1]], [[1uzw]], [[1w03]], [[1w05]], [[2bu9]], [[1w3v]], [[1w3x]], [[2ivi]], [[2ivj]], [[2vau]], [[2vbb]], [[2vbd]], [[2vbp]], [[2vcm]], [[2ve1]], [[2wo7]], [[2y6f]], [[2y60]], [[2y86]] - AnIPNS + ACV derivative<br />
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[[2jb4]] - AnIPNS + cyclobutanone analog<br />
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**[[2jb4]] - AnIPNS + cyclobutanone analog<br />
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[[1qje]] - AnIPNS + IPN + ACV<br />
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**[[1qje]] - AnIPNS + IPN + ACV<br />
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[[1blz]] - AnIPNS + NO + ACV<br />
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**[[1blz]] - AnIPNS + NO + ACV<br />
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[[1obn]], [[1w04]], [[1w06]] - AnIPNS + hydroxylamine + ACV derivative
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**[[1obn]], [[1w04]], [[1w06]] - AnIPNS + hydroxylamine + ACV derivative
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===Mn containing IPNS===
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*Mn containing IPNS
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[[1ips]] – AnIPNS
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**[[1ips]] – AnIPNS
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}}
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[[Category: Topic Page]]

Revision as of 08:50, 30 November 2014

Template:STRUCTURE 1blz

Isopenicillin N synthase (IPNS) is an iron-dependent enzyme which catalyzes the formation of isopenicillin N (IPN) from the tripeptide aminoadipoyl-cysteine-valine (ACV). IPNS participates in the biosynthesis of penicillin and cephalosporin antibiotics. The active site of IPNS contains an Fe atom. The reaction involves the reduction of O2 molecule to H2O.

3D structures of isopenicillin N synthase

Updated on 30-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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