4hj2

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'''Unreleased structure'''
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{{STRUCTURE_4hj2| PDB=4hj2 | SCENE= }}
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===Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil===
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{{ABSTRACT_PUBMED_23460799}}
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The entry 4hj2 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:20606271</ref>
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Authors: Karpusas, M., Chiniadis, L., Labrou, N.E.
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==About this Structure==
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[[4hj2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ2 OCA].
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Description: Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Glutathione transferase]]
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[[Category: Homo sapiens]]
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[[Category: Chiniadis, L.]]
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[[Category: Karpusas, M.]]
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[[Category: Labrou, N E.]]
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[[Category: Alpha-beta]]
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[[Category: Transferase]]

Revision as of 08:45, 27 March 2013

Template:STRUCTURE 4hj2

Contents

Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil

Template:ABSTRACT PUBMED 23460799

Function

[GSTA1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.[1]

About this Structure

4hj2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Achilonu I, Gildenhuys S, Fisher L, Burke J, Fanucchi S, Sewell BT, Fernandes M, Dirr HW. The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jul 1;66(Pt, 7):776-80. Epub 2010 Jun 23. PMID:20606271 doi:10.1107/S1744309110019135

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