1qs3

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[[Image:1qs3.png|left|200px]]
 
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{{STRUCTURE_1qs3| PDB=1qs3 | SCENE= }}
{{STRUCTURE_1qs3| PDB=1qs3 | SCENE= }}
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===NMR SOLUTION CONFORMATION OF AN ANTITOXIC ANALOG OF ALPHA-CONOTOXIN GI===
===NMR SOLUTION CONFORMATION OF AN ANTITOXIC ANALOG OF ALPHA-CONOTOXIN GI===
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{{ABSTRACT_PUBMED_10508392}}
{{ABSTRACT_PUBMED_10508392}}
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==Function==
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[[http://www.uniprot.org/uniprot/CA1A_CONGE CA1A_CONGE]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. The higher affinity site for alpha-conotoxin GI is the alpha/delta site on mouse muscle-derived BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from Torpedo californica electric organ.
==About this Structure==
==About this Structure==
[[1qs3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QS3 OCA].
[[1qs3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QS3 OCA].
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==Reference==
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<ref group="xtra">PMID:010508392</ref><references group="xtra"/><references/>
[[Category: Han, K H.]]
[[Category: Han, K H.]]
[[Category: Mok, K H.]]
[[Category: Mok, K H.]]

Revision as of 14:13, 12 March 2014

Template:STRUCTURE 1qs3

Contents

NMR SOLUTION CONFORMATION OF AN ANTITOXIC ANALOG OF ALPHA-CONOTOXIN GI

Template:ABSTRACT PUBMED 10508392

Function

[CA1A_CONGE] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. The higher affinity site for alpha-conotoxin GI is the alpha/delta site on mouse muscle-derived BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from Torpedo californica electric organ.

About this Structure

1qs3 is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Mok KH, Han KH. NMR solution conformation of an antitoxic analogue of alpha-conotoxin GI: identification of a common nicotinic acetylcholine receptor alpha 1-subunit binding surface for small ligands and alpha-conotoxins. Biochemistry. 1999 Sep 14;38(37):11895-904. PMID:10508392

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