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Glycogen synthase kinase 3

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===3D structures of glycogen synthase kinase 3===
===3D structures of glycogen synthase kinase 3===
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
[[1i09]], [[1h8f]] – hGSK-3 β – human<br />
[[1i09]], [[1h8f]] – hGSK-3 β – human<br />

Revision as of 08:45, 10 March 2013

Template:STRUCTURE 4dit

Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase. GSK-3 is active in a number of intracellular signaling pathways. GSK-3 regulates glycogen synthase as well as other proteins. GSK-3 inhibition is studied as a therapeutic target in diseases like Alzheimer, diabetes, bipolar disorder and some cancers.

3D structures of glycogen synthase kinase 3

Updated on 10-March-2013

1i09, 1h8f – hGSK-3 β – human
1gng - hGSK-3 β + Frattide peptide
1o9u - hGSK-3 β + Axin peptide
1q4l, 1uv5, 1q5k, 1r0e, 2o5k, 2ow3, 3du8, 3f7z, 3f88, 3i4b, 3gb2, 3l1s, 3q3b, 3zrk, 3zrl, 3zrm, 3sd0, 4dit, 4afj, 4acc, 4acd, 4acg, 4ach, 3say - hGSK-3 β + inhibitor
1pyx, 1j1b - hGSK-3 β + AMPPNP
1j1c - hGSK-3 β + ADP
1q3d, 1q3w, 1q41 - hGSK-3 β + ATP-mimetic inhibitor
2jld - hGSK-3 β + Ru complex + peptide
3m1s, 3pup - hGSK-3 β + Ru complex
3zdi - hGSK-3 β + Axin peptide + inhibitor

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Michal Harel, Alexander Berchansky

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