1siv

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Revision as of 10:52, 4 January 2013

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Template:STRUCTURE 1siv

THREE-DIMENSIONAL STRUCTURE OF A SIV PROTEASE(SLASH)INHIBITOR COMPLEX. IMPLICATIONS FOR THE DESIGN OF HIV-1 AND HIV-2 PROTEASE INHIBITORS

Template:ABSTRACT PUBMED 8241159

About this Structure

1siv is a 2 chain structure with sequence from Simian immunodeficiency virus. Full crystallographic information is available from OCA.

Reference

• Zhao B, Winborne E, Minnich MD, Culp JS, Debouck C, Abdel-Meguid SS. Three-dimensional structure of a simian immunodeficiency virus protease/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 protease inhibitors. Biochemistry. 1993 Dec 7;32(48):13054-60. PMID:8241159
• Ishima R, Louis JM, Torchia DA. Characterization of two hydrophobic methyl clusters in HIV-1 protease by NMR spin relaxation in solution. J Mol Biol. 2001 Jan 19;305(3):515-21. PMID:11152609 doi:10.1006/jmbi.2000.4321