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From Proteopedia
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<Structure load='1UWH' size='400' frame='true' align='left' caption='3D View of the complex' scene='Insert optional scene name here' /> | <Structure load='1UWH' size='400' frame='true' align='left' caption='3D View of the complex' scene='Insert optional scene name here' /> | ||
| - | [[Image:1-s2.0-S0092867404002156-main page7 image1.jpg|400px|thumb| A. Structure of B-RAF Kinase Domain | + | [[Image:1-s2.0-S0092867404002156-main page7 image1.jpg|400px|thumb| A. Structure of B-RAF Kinase Domain <br /> |
B. Schematic B-RAF Primary Structure]] | B. Schematic B-RAF Primary Structure]] | ||
Blablastructurepdb | Blablastructurepdb | ||
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drugs and inhibitor paradox | drugs and inhibitor paradox | ||
| - | == | + | == Applications in Medicine == |
== External Ressources == | == External Ressources == | ||
Revision as of 14:24, 4 January 2013
The complex of wild type B-RAF and BAY439006
Contents |
Introduction
Structure[1]
|
B. Schematic B-RAF Primary Structure
Blablastructurepdb
Regulation
signaling ways
Other Inhibitors
drugs and inhibitor paradox
Applications in Medicine
External Ressources
References
- ↑ Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. PMID:15035987
Protreopedia Page Contributors and Editors
Kostika Sofroni and Gilles Dupouy
