1uwj
From Proteopedia
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{{STRUCTURE_1uwj| PDB=1uwj | SCENE= }} | {{STRUCTURE_1uwj| PDB=1uwj | SCENE= }} | ||
| - | === | + | ===The complex of mutant V599E B-RAF and BAY439006=== |
{{ABSTRACT_PUBMED_15035987}} | {{ABSTRACT_PUBMED_15035987}} | ||
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<ref group="xtra">PMID:015035987</ref><references group="xtra"/> | <ref group="xtra">PMID:015035987</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Barford, D.]] | [[Category: Barford, D.]] | ||
[[Category: Project, Cancer Genome]] | [[Category: Project, Cancer Genome]] | ||
[[Category: Roe, S M.]] | [[Category: Roe, S M.]] | ||
[[Category: Wan, P T.C.]] | [[Category: Wan, P T.C.]] | ||
| - | [[Category: Kinase]] | ||
[[Category: Signal transduction]] | [[Category: Signal transduction]] | ||
[[Category: Threonine-protein kinase]] | [[Category: Threonine-protein kinase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 09:16, 16 January 2013
The complex of mutant V599E B-RAF and BAY439006
Template:ABSTRACT PUBMED 15035987
About this Structure
1uwj is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. PMID:15035987
