1tq1

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[[Image:1tq1.png|left|200px]]
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==Solution structure of At5g66040, a putative protein from Arabidosis Thaliana==
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<StructureSection load='1tq1' size='340' side='right' caption='[[1tq1]], [[NMR_Ensembles_of_Models | 5 NMR models]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1tq1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TQ1 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tq1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tq1 RCSB], [http://www.ebi.ac.uk/pdbsum/1tq1 PDBsum], [http://www.topsan.org/Proteins/CESG/1tq1 TOPSAN]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tq/1tq1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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We describe the three-dimensional structure of the product of Arabidopsis thaliana gene At5g66040.1 as determined by NMR spectroscopy. This protein is categorized as single-domain sulfurtransferase and is annotated as a senescence-associated protein (sen1-like protein) and ketoconazole resistance protein (http://arabidopsis.org/info/genefamily/STR_genefamily.html). The sequence of At5g66040.1 is virtually identical to that of a protein from Arabidopsis found by others to confer ketoconazole resistance in yeast. Comparison of the three-dimensional structure with those in the Protein Data Bank revealed that At5g66040.1 contains an additional mobile beta-hairpin not found in other rhodaneses that may function in binding specific substrates. This represents the first structure of a single-domain plant sulfurtransferase. The enzymatically active cysteine-containing domain belongs to the CDC25 class of phosphatases, sulfide dehydrogenases, and stress proteins such as senescence specific protein 1 in plants, PspE and GlpE in bacteria, and cyanide and arsenate resistance proteins. Versions of this domain that lack the active site cysteine are found in other proteins, such as phosphatases, ubiquitin hydrolases, and sulfuryltransferases.
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{{STRUCTURE_1tq1| PDB=1tq1 | SCENE= }}
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Solution structure of a single-domain thiosulfate sulfurtransferase from Arabidopsis thaliana.,Cornilescu G, Vinarov DA, Tyler EM, Markley JL, Cornilescu CC Protein Sci. 2006 Dec;15(12):2836-41. Epub 2006 Nov 6. PMID:17088324<ref>PMID:17088324</ref>
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===Solution structure of At5g66040, a putative protein from Arabidosis Thaliana===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_17088324}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1tq1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQ1 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:017088324</ref><references group="xtra"/>
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]

Revision as of 19:29, 29 September 2014

Solution structure of At5g66040, a putative protein from Arabidosis Thaliana

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