1wn0

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[[Image:1wn0.png|left|200px]]
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==Crystal Structure of Histidine-containing Phosphotransfer Protein, ZmHP2, from maize==
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<StructureSection load='1wn0' size='340' side='right' caption='[[1wn0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1wn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WN0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oxb|1oxb]], [[2a0b|2a0b]], [[1i5n|1i5n]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Zmhp2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4577 Zea mays])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wn0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wn0 PDBsum], [http://www.topsan.org/Proteins/RSGI/1wn0 TOPSAN]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/1wn0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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In higher plants, histidine-aspartate phosphorelays (two-component system) are involved in hormone signaling and stress responses. In these systems, histidine-containing phosphotransfer (HPt) proteins mediate the signal transmission from sensory histidine kinases to response regulators, including integration of several signaling pathways or branching into different pathways. We have determined the crystal structure of a maize HPt protein, ZmHP2, at 2.2 A resolution. ZmHP2 has six alpha-helices with a four-helix bundle at the C-terminus, a feature commonly found in HPt domains. In ZmHP2, almost all of the conserved residues among plant HPt proteins surround this histidine, probably forming the docking interface for the receiver domain of histidine kinase or the response regulator. Arg102 of ZmHP2 is conserved as a basic residue in plant HPt proteins. In bacteria, it is replaced by glutamine or glutamate that form a hydrogen bond to Ndelta atoms of the phospho-accepting histidine. It may play a key role in the complex formation of ZmHP2 with receiver domains.
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{{STRUCTURE_1wn0| PDB=1wn0 | SCENE= }}
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Crystal structure of the histidine-containing phosphotransfer protein ZmHP2 from maize.,Sugawara H, Kawano Y, Hatakeyama T, Yamaya T, Kamiya N, Sakakibara H Protein Sci. 2005 Jan;14(1):202-8. Epub 2004 Dec 2. PMID:15576555<ref>PMID:15576555</ref>
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===Crystal Structure of Histidine-containing Phosphotransfer Protein, ZmHP2, from maize===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_15576555}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1wn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WN0 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015576555</ref><references group="xtra"/>
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[[Category: Zea mays]]
[[Category: Zea mays]]
[[Category: Hatakeyama, T.]]
[[Category: Hatakeyama, T.]]

Revision as of 21:46, 29 September 2014

Crystal Structure of Histidine-containing Phosphotransfer Protein, ZmHP2, from maize

1wn0, resolution 2.20Å

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