1upx

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[[Image:1upx.jpg|left|200px]]<br /><applet load="1upx" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1upx.jpg|left|200px]]
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caption="1upx, resolution 1.25&Aring;" />
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'''THE CRYSTAL STRUCTURE OF THE HYBRID CLUSTER PROTEIN FROM DESULFOVIBRIO DESULFURICANS CONTAINING MOLECULES IN THE OXIDIZED AND REDUCED STATES.'''<br />
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{{Structure
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|PDB= 1upx |SIZE=350|CAPTION= <scene name='initialview01'>1upx</scene>, resolution 1.25&Aring;
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|SITE= <scene name='pdbsite=AC1:Mes+Binding+Site+For+Chain+B'>AC1</scene>
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|LIGAND= <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SF3:FE4-S3+CLUSTER'>SF3</scene>, <scene name='pdbligand=FSO:IRON/SULFUR/OXYGEN+HYBRID+CLUSTER'>FSO</scene> and <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC ACID'>MES</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''THE CRYSTAL STRUCTURE OF THE HYBRID CLUSTER PROTEIN FROM DESULFOVIBRIO DESULFURICANS CONTAINING MOLECULES IN THE OXIDIZED AND REDUCED STATES.'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1UPX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans] with <scene name='pdbligand=SF4:'>SF4</scene>, <scene name='pdbligand=SF3:'>SF3</scene>, <scene name='pdbligand=FSO:'>FSO</scene> and <scene name='pdbligand=MES:'>MES</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:Mes+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UPX OCA].
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1UPX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UPX OCA].
==Reference==
==Reference==
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Structure of the hybrid cluster protein (HCP) from Desulfovibrio desulfuricans ATCC 27774 containing molecules in the oxidized and reduced states., Macedo S, Aragao D, Mitchell EP, Lindley P, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2065-71. Epub 2003, Nov 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14646063 14646063]
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Structure of the hybrid cluster protein (HCP) from Desulfovibrio desulfuricans ATCC 27774 containing molecules in the oxidized and reduced states., Macedo S, Aragao D, Mitchell EP, Lindley P, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2065-71. Epub 2003, Nov 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14646063 14646063]
[[Category: Desulfovibrio desulfuricans]]
[[Category: Desulfovibrio desulfuricans]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: SF3]]
[[Category: SF3]]
[[Category: SF4]]
[[Category: SF4]]
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[[Category: desulfovibrio desulfuricans]]
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[[Category: desulfovibrio desulfurican]]
[[Category: high-resolution]]
[[Category: high-resolution]]
[[Category: hybrid cluster]]
[[Category: hybrid cluster]]
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[[Category: sulphur]]
[[Category: sulphur]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:27:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:35:20 2008''

Revision as of 12:35, 20 March 2008

Image:1upx.jpg


PDB ID 1upx

Drag the structure with the mouse to rotate
, resolution 1.25Å
Sites:
Ligands: , , and
Coordinates: save as pdb, mmCIF, xml



THE CRYSTAL STRUCTURE OF THE HYBRID CLUSTER PROTEIN FROM DESULFOVIBRIO DESULFURICANS CONTAINING MOLECULES IN THE OXIDIZED AND REDUCED STATES.


Overview

The hybrid cluster protein (HCP) from the sulfate-reducing bacteria Desulfovibrio desulfuricans ATCC 27774 has been isolated and crystallized anaerobically. The protein sample used in the crystallization studies was several months old, having been stored at 193 K, and initial crystal structure studies were unable to fully resolve details of the hybrid cluster despite the use of high-resolution data to 1.25 A collected at the ESRF, Grenoble, France. Full elucidation of the structure has only become possible with the complete knowledge of the as-isolated and fully reduced crystal structures. The analysis clarifies the significant movements in the position of the Fe atom linked to the persulfide moiety in the oxidized as-isolated protein and the S atom of the persulfide itself as the protein is reduced. The structures of the as-isolated and reduced states are discussed in terms of the putative function of the HCP proteins.

About this Structure

1UPX is a Single protein structure of sequence from Desulfovibrio desulfuricans. Full crystallographic information is available from OCA.

Reference

Structure of the hybrid cluster protein (HCP) from Desulfovibrio desulfuricans ATCC 27774 containing molecules in the oxidized and reduced states., Macedo S, Aragao D, Mitchell EP, Lindley P, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2065-71. Epub 2003, Nov 27. PMID:14646063

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