2b7z

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[[Image:2b7z.png|left|200px]]
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==Structure of HIV-1 protease mutant bound to indinavir==
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<StructureSection load='2b7z' size='340' side='right' caption='[[2b7z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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{{STRUCTURE_2b7z| PDB=2b7z | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2b7z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B7Z FirstGlance]. <br>
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===Structure of HIV-1 protease mutant bound to indinavir===
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MK1:N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY+BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE'>MK1</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b60|2b60]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b7z RCSB], [http://www.ebi.ac.uk/pdbsum/2b7z PDBsum]</span></td></tr>
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==About this Structure==
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<table>
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[[2b7z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7Z OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/2b7z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Agbandje-McKenna, M.]]
[[Category: Agbandje-McKenna, M.]]

Revision as of 23:55, 29 September 2014

Structure of HIV-1 protease mutant bound to indinavir

2b7z, resolution 2.20Å

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