2a3w

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2a3w" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:2a3w.png|left|200px]]
 
- 
{{STRUCTURE_2a3w| PDB=2a3w | SCENE= }}
{{STRUCTURE_2a3w| PDB=2a3w | SCENE= }}
- 
===Decameric structure of human serum amyloid P-component bound to Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane===
===Decameric structure of human serum amyloid P-component bound to Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane===
 +
{{ABSTRACT_PUBMED_16036920}}
-
{{ABSTRACT_PUBMED_16036920}}
+
==Disease==
 +
[[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
 +
 
 +
==Function==
 +
[[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
==About this Structure==
==About this Structure==
Line 11: Line 13:
==Reference==
==Reference==
-
<ref group="xtra">PMID:016036920</ref><references group="xtra"/>
+
<ref group="xtra">PMID:016036920</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bundle, D R.]]
[[Category: Bundle, D R.]]

Revision as of 19:41, 24 March 2013

Template:STRUCTURE 2a3w

Contents

Decameric structure of human serum amyloid P-component bound to Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane

Template:ABSTRACT PUBMED 16036920

Disease

[SAMP_HUMAN] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.

Function

[SAMP_HUMAN] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.

About this Structure

2a3w is a 20 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ho JG, Kitov PI, Paszkiewicz E, Sadowska J, Bundle DR, Ng KK. Ligand-assisted aggregation of proteins. Dimerization of serum amyloid P component by bivalent ligands. J Biol Chem. 2005 Sep 9;280(36):31999-2008. Epub 2005 Jul 20. PMID:16036920 doi:10.1074/jbc.M504403200

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2a3w"
Personal tools