1v39

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1v39.gif|left|200px]]<br /><applet load="1v39" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1v39.gif|left|200px]]
-
caption="1v39, resolution 1.8&Aring;" />
+
 
-
'''DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG'''<br />
+
{{Structure
 +
|PDB= 1v39 |SIZE=350|CAPTION= <scene name='initialview01'>1v39</scene>, resolution 1.8&Aring;
 +
|SITE=
 +
|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> and <scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE'>M7G</scene>
 +
|ACTIVITY= [http://en.wikipedia.org/wiki/Polynucleotide_adenylyltransferase Polynucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.19 2.7.7.19]
 +
|GENE=
 +
}}
 +
 
 +
'''DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1V39 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus] with <scene name='pdbligand=SAH:'>SAH</scene> and <scene name='pdbligand=M7G:'>M7G</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Polynucleotide_adenylyltransferase Polynucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.19 2.7.7.19] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V39 OCA].
+
1V39 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V39 OCA].
==Reference==
==Reference==
-
Specific protein recognition of an mRNA cap through its alkylated base., Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA, Nat Struct Biol. 1997 May;4(5):350-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9145102 9145102]
+
Specific protein recognition of an mRNA cap through its alkylated base., Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA, Nat Struct Biol. 1997 May;4(5):350-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9145102 9145102]
[[Category: Polynucleotide adenylyltransferase]]
[[Category: Polynucleotide adenylyltransferase]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 26: Line 35:
[[Category: vaccinia]]
[[Category: vaccinia]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:31:03 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:40:15 2008''

Revision as of 12:40, 20 March 2008


PDB ID 1v39

Drag the structure with the mouse to rotate
, resolution 1.8Å
Ligands: and
Activity: Polynucleotide adenylyltransferase, with EC number 2.7.7.19
Coordinates: save as pdb, mmCIF, xml



DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG


Overview

The specific binding of N7-methylguanine cap analogues to the RNA methyltransferase VP39 was observed through X-ray crystallography, providing a prototypical structure for a complex between a protein and an mRNA 5' cap.

About this Structure

1V39 is a Single protein structure of sequence from Vaccinia virus. Full crystallographic information is available from OCA.

Reference

Specific protein recognition of an mRNA cap through its alkylated base., Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA, Nat Struct Biol. 1997 May;4(5):350-4. PMID:9145102

Page seeded by OCA on Thu Mar 20 14:40:15 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools