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2pr9

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Revision as of 10:24, 7 January 2013

Image:2pr9.png

Template:STRUCTURE 2pr9

Mu2 adaptin subunit (AP50) of AP2 adaptor (second domain), complexed with GABAA receptor-gamma2 subunit-derived internalization peptide DEEYGYECL

Template:ABSTRACT PUBMED 18305175

About this Structure

2pr9 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Kittler JT, Chen G, Kukhtina V, Vahedi-Faridi A, Gu Z, Tretter V, Smith KR, McAinsh K, Arancibia-Carcamo IL, Saenger W, Haucke V, Yan Z, Moss SJ. Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor gamma2 subunit. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3616-21. Epub 2008 Feb 27. PMID:18305175
  • Traub LM. Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol. 2009 Sep;10(9):583-96. PMID:19696796 doi:10.1038/nrm2751

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OCA

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