2kw6
From Proteopedia
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{{STRUCTURE_2kw6| PDB=2kw6 | SCENE= }} | {{STRUCTURE_2kw6| PDB=2kw6 | SCENE= }} | ||
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===Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H=== | ===Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H=== | ||
| + | {{ABSTRACT_PUBMED_22427660}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/CDKA1_HUMAN CDKA1_HUMAN]] specific inhibitor of the cell-cycle kinase CDK2 (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[2kw6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KW6 OCA]. | [[2kw6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KW6 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022427660</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Acton, T B.]] | [[Category: Acton, T B.]] | ||
Revision as of 05:56, 2 October 2013
Contents |
Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H
Template:ABSTRACT PUBMED 22427660
Function
[CDKA1_HUMAN] specific inhibitor of the cell-cycle kinase CDK2 (By similarity).
About this Structure
2kw6 is a 2 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Ertekin A, Aramini JM, Rossi P, Leonard PG, Janjua H, Xiao R, Maglaqui M, Lee HW, Prestegard JH, Montelione GT. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region. J Biol Chem. 2012 May 11;287(20):16541-9. Epub 2012 Mar 14. PMID:22427660 doi:10.1074/jbc.M112.343863
Categories: Homo sapiens | Acton, T B. | Aramini, J M. | Ciccosanti, C T. | Ertekin, A. | Everett, J K. | Jiang, M. | Lee, A B. | Montelione, G T. | NESG, Northeast Structural Genomics Consortium. | Prestegard, J H. | Rossi, P. | Rost, B. | Swapna, G V.T. | Xiao, R. | Cancer suppressor | Cell cycle | Protein structure initiative | Psi-2 | Structural genomic
