2hto

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[[Image:2hto.png|left|200px]]
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==Ruthenium hexammine ion interactions with Z-DNA==
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<StructureSection load='2hto' size='340' side='right' caption='[[2hto]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2hto]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HTO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRU:RUTHENIUM+(III)+HEXAAMINE+ION'>NRU</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2htt|2htt]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hto OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hto RCSB], [http://www.ebi.ac.uk/pdbsum/2hto PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.
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{{STRUCTURE_2hto| PDB=2hto | SCENE= }}
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Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080<ref>PMID:18084080</ref>
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===Ruthenium hexammine ion interactions with Z-DNA===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_18084080}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2hto]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTO OCA].
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</StructureSection>
[[Category: Bharanidharan, D.]]
[[Category: Bharanidharan, D.]]
[[Category: Gautham, N.]]
[[Category: Gautham, N.]]

Revision as of 15:35, 12 October 2014

Ruthenium hexammine ion interactions with Z-DNA

2hto, resolution 1.54Å

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