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2hto
From Proteopedia
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| - | [[ | + | ==Ruthenium hexammine ion interactions with Z-DNA== |
| + | <StructureSection load='2hto' size='340' side='right' caption='[[2hto]], [[Resolution|resolution]] 1.54Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2hto]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HTO FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRU:RUTHENIUM+(III)+HEXAAMINE+ION'>NRU</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2htt|2htt]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hto OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hto RCSB], [http://www.ebi.ac.uk/pdbsum/2hto PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity. | ||
| - | + | Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080<ref>PMID:18084080</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | + | </StructureSection> | |
[[Category: Bharanidharan, D.]] | [[Category: Bharanidharan, D.]] | ||
[[Category: Gautham, N.]] | [[Category: Gautham, N.]] | ||
Revision as of 15:35, 12 October 2014
Ruthenium hexammine ion interactions with Z-DNA
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